<https://www.sib.swiss/> 	<https://www.biozentrum.unibas.ch/> 	
SWISS-MODEL Homology Modelling Report


    Model Building Report

This document lists the results for the homology modelling project
"Ice2" submitted to SWISS-MODEL workspace on Feb. 20, 2021, 2:11
p.m..The submitted primary amino acid sequence is given in Table T1.

If you use any results in your research, please cite the relevant
publications:

  * Waterhouse, A., Bertoni, M., Bienert, S., Studer, G., Tauriello, G.,
    Gumienny, R., Heer, F.T., de Beer, T.A.P., Rempfer, C., Bordoli, L.,
    Lepore, R., Schwede, T. SWISS-MODEL: homology modelling of protein
    structures and complexes. Nucleic Acids Res. 46(W1), W296-W303
    (2018). <https://pubmed.ncbi.nlm.nih.gov/29788355>
    <https://dx.doi.org/10.1093/nar/gky427>
  * Bienert, S., Waterhouse, A., de Beer, T.A.P., Tauriello, G., Studer,
    G., Bordoli, L., Schwede, T. The SWISS-MODEL Repository - new
    features and functionality. Nucleic Acids Res. 45, D313-D319 (2017).
    <https://pubmed.ncbi.nlm.nih.gov/27899672>
    <https://dx.doi.org/10.1093/nar/gkw1132>
  * Studer, G., Tauriello, G., Bienert, S., Biasini, M., Johner, N.,
    Schwede, T. ProMod3 - A versatile homology modelling toolbox. PLOS
    Comp. Biol. 17(1), e1008667 (2021).
    <https://pubmed.ncbi.nlm.nih.gov/33507980>
    <https://doi.org/10.1371/journal.pcbi.1008667>
  * Studer, G., Rempfer, C., Waterhouse, A.M., Gumienny, G., Haas, J.,
    Schwede, T. QMEANDisCo - distance constraints applied on model
    quality estimation. Bioinformatics 36, 1765-1771 (2020).
    <https://pubmed.ncbi.nlm.nih.gov/31697312>
    <https://dx.doi.org/10.1093/bioinformatics/btz828>
  * Bertoni, M., Kiefer, F., Biasini, M., Bordoli, L., Schwede, T.
    Modeling protein quaternary structure of homo- and hetero-oligomers
    beyond binary interactions by homology. Scientific Reports 7 (2017).
    <https://pubmed.ncbi.nlm.nih.gov/28874689>
    <https://dx.doi.org/10.1038/s41598-017-09654-8>


    Results

The SWISS-MODEL template library (SMTL version 2021-02-17, PDB release
2021-02-12) was searched with BLAST (Camacho et al. <#blastp>) and
HHblits (Steinegger et al. <#hhblits>) for evolutionary related
structures matching the target sequence in Table T1. For details on the
template search, see Materials and Methods. Overall 19 templates were
found (Table T2).


    Models

The following models were built (see Materials and Methods "Model
Building"):


      Model #01

	File 	Built with 	Oligo-State 	Ligands 	GMQE 	QMEAN
<https://swissmodel.expasy.org/interactive/3DmTPB/models/01.png> 	PDB
<https://swissmodel.expasy.org/interactive/3DmTPB/models/01.pdb>
ProMod3 3.2.0 	monomer 	
None
	0.08 	-4.56

QMEAN	
Created with Raphaël 2.2.0
	-4.56
Cβ	
Created with Raphaël 2.2.0
	-4.60
All Atom	
Created with Raphaël 2.2.0
	-0.23
solvation	
Created with Raphaël 2.2.0
	-1.56
torsion	
Created with Raphaël 2.2.0
	-3.24

	
Created with Raphaël 2.2.0Residue Number
<#lq-chart-01> Created with Raphaël 2.2.0Local Quality EstimatePredicted
Local Similarity to TargetResidue
Number1.00.80.60.40.20.0150160170180190200210220230240250260
	
Created with Raphaël 2.2.0★Protein Size (Residues)
<#qn-chart-01> Created with Raphaël 2.2.0★Comparison with Non-redundant
Set of PDB StructuresNormalized QMEAN4 ScoreProtein Size
(Residues)1002003004005000.00.51.01.5

Template 	Seq Identity 	Oligo-state 	QSQE 	Found by 	Method
Resolution 	Seq Similarity 	Range 	Coverage 	Description
6sp2.1.A <https://swissmodel.expasy.org/templates/6sp2.1> 	15.25
monomer 	0.00 	HHblits 	EM 	- 	0.27 	142 - 263 	0.24 	Membrane protein
TMS1d


      Excluded ligands

Ligand Name.Number 	Reason for Exclusion 	Description
CDL.3	Binding site not conserved. 	
CARDIOLIPIN
CDL.5	Binding site not conserved. 	
CARDIOLIPIN
CDL.9	Binding site not conserved. 	
CARDIOLIPIN
CDL.13	Binding site not conserved. 	
CARDIOLIPIN
CDL.17	Binding site not conserved. 	
CARDIOLIPIN
CDL.21	Binding site not conserved. 	
CARDIOLIPIN
LMN.1	Binding site not conserved. 	
Lauryl Maltose Neopentyl Glycol
LMN.4	Binding site not conserved. 	
Lauryl Maltose Neopentyl Glycol
LMN.6	Binding site not conserved. 	
Lauryl Maltose Neopentyl Glycol
LMN.7	Binding site not conserved. 	
Lauryl Maltose Neopentyl Glycol
LMN.10	Binding site not conserved. 	
Lauryl Maltose Neopentyl Glycol
LMN.11	Binding site not conserved. 	
Lauryl Maltose Neopentyl Glycol
LMN.14	Binding site not conserved. 	
Lauryl Maltose Neopentyl Glycol
LMN.15	Binding site not conserved. 	
Lauryl Maltose Neopentyl Glycol
LMN.18	Binding site not conserved. 	
Lauryl Maltose Neopentyl Glycol
LMN.19	Binding site not conserved. 	
Lauryl Maltose Neopentyl Glycol
LMN.22	Binding site not conserved. 	
Lauryl Maltose Neopentyl Glycol
LMN.23	Binding site not conserved. 	
Lauryl Maltose Neopentyl Glycol
P5S.2	Binding site not conserved. 	
O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine
P5S.8	Binding site not conserved. 	
O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine
P5S.12	Binding site not conserved. 	
O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine
P5S.16	Binding site not conserved. 	
O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine
P5S.20	Binding site not conserved. 	
O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine
P5S.24	Binding site not conserved. 	
O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine


Target    MTSLSKSFMQSGRICAACFYLLFTLLSIPISFKVGGLECGLSFTVTLFTLYFITTTLNVLARRHGGRLYIFFTNCLYYSQ
6sp2.1.A  --------------------------------------------------------------------------------

Target    HFIIASLLYLFLSGFSNDELGNVLKNKYNESESFLEALKNSLNSNQINYVLYYYYYRFVVQPWQFVLTKSTPFFTLSEGF
6sp2.1.A  -------------------------------------------------------------AMMWVGLIGGLAFILVQLV

Target    FTILAIQAVGETNRWLSNDLNSNTWIISSLLTSGGVITASLYY---LYRIYVTPIWPLSIQTASLLGLVLSMVCGLGLYG
6sp2.1.A  IIVDFAHSLAE--NWIESAENSRGYYYALAGVTLLCYILSLTGITLLYIYFT-TS-TGCGINKFFISINLIFCLAISVIS

Target    IV------SQKGSVIESSLFFAYIVRCIYEISPKLATTATDEILNLFKDVWQKHQRNLPTADNLLCYFHNVILKNAEVLW
6sp2.1.A  ILPAVQERLPHSGLLQSSLVTLYTVYLTWSAV------------------------------------------------

Target    GSFIPRGRKKTGDFHDKLISILSFEKVSLISKPFWKFFKNFTFSVPLSINEFCQVTIKMASESVSPAIVINLCFRVLMFY
6sp2.1.A  --------------------------------------------------------------------------------

Target    SATRIIPALQRKNDKQLRKSRRIMKGLYWYSPCILIAMYTHLILQYSGELKKDLCIWGCSEKWFGVDQPEIIVDSWGFWN
6sp2.1.A  --------------------------------------------------------------------------------

Target    WCNIFCTILVYATELIGSGS
6sp2.1.A  --------------------


------------------------------------------------------------------------


      Model #02

	File 	Built with 	Oligo-State 	Ligands 	GMQE 	QMEAN
<https://swissmodel.expasy.org/interactive/3DmTPB/models/02.png> 	PDB
<https://swissmodel.expasy.org/interactive/3DmTPB/models/02.pdb>
ProMod3 3.2.0 	monomer 	
None
	0.04 	-5.79

QMEAN	
Created with Raphaël 2.2.0
	-5.79
Cβ	
Created with Raphaël 2.2.0
	-3.63
All Atom	
Created with Raphaël 2.2.0
	-1.75
solvation	
Created with Raphaël 2.2.0
	-2.50
torsion	
Created with Raphaël 2.2.0
	-4.02

	
Created with Raphaël 2.2.0Residue Number
<#lq-chart-02> Created with Raphaël 2.2.0Local Quality EstimatePredicted
Local Similarity to TargetResidue Number1.00.80.60.40.20.01020304050607080
	
Created with Raphaël 2.2.0★Protein Size (Residues)
<#qn-chart-02> Created with Raphaël 2.2.0★Comparison with Non-redundant
Set of PDB StructuresNormalized QMEAN4 ScoreProtein Size
(Residues)1002003004005000.00.51.01.5

Template 	Seq Identity 	Oligo-state 	QSQE 	Found by 	Method
Resolution 	Seq Similarity 	Range 	Coverage 	Description
6v4l.1.E <https://swissmodel.expasy.org/templates/6v4l.1> 	18.75
monomer 	0.00 	HHblits 	X-ray 	3.80Å 	0.27 	10 - 89 	0.16 	Trk system
potassium uptake protein TrkH


      Excluded ligands

Ligand Name.Number 	Reason for Exclusion 	Description
AGS.1	Binding site not conserved. 	
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
AGS.2	Binding site not conserved. 	
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
AGS.3	Binding site not conserved. 	
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
AGS.4	Binding site not conserved. 	
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
AGS.5	Binding site not conserved. 	
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
AGS.6	Binding site not conserved. 	
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
AGS.7	Binding site not conserved. 	
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
AGS.8	Binding site not conserved. 	
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER


Target    MTSLSKSFMQSGRICAACFYLLFTLLSIPISFKVG-GLECGLSFTVTLFTLYFITTTLNVLARRHGGRLYIFFTNCLYYS
6v4l.1.E  ---------SIIRIVGLLLALFSVTMLAPALVALLYRDGAGVPFVTTFFVLLFCGAMCWFPNRRHKHELKSRDGFLIVVL

Target    QHFIIASLLYLFLSGFSNDELGNVLKNKYNESESFLEALKNSLNSNQINYVLYYYYYRFVVQPWQFVLTKSTPFFTLSEG
6v4l.1.E  FWTVLGSAGS----------------------------------------------------------------------

Target    FFTILAIQAVGETNRWLSNDLNSNTWIISSLLTSGGVITASLYYLYRIYVTPIWPLSIQTASLLGLVLSMVCGLGLYGIV
6v4l.1.E  --------------------------------------------------------------------------------

Target    SQKGSVIESSLFFAYIVRCIYEISPKLATTATDEILNLFKDVWQKHQRNLPTADNLLCYFHNVILKNAEVLWGSFIPRGR
6v4l.1.E  --------------------------------------------------------------------------------

Target    KKTGDFHDKLISILSFEKVSLISKPFWKFFKNFTFSVPLSINEFCQVTIKMASESVSPAIVINLCFRVLMFYSATRIIPA
6v4l.1.E  --------------------------------------------------------------------------------

Target    LQRKNDKQLRKSRRIMKGLYWYSPCILIAMYTHLILQYSGELKKDLCIWGCSEKWFGVDQPEIIVDSWGFWNWCNIFCTI
6v4l.1.E  --------------------------------------------------------------------------------

Target    LVYATELIGSGS
6v4l.1.E  ------------


------------------------------------------------------------------------


      Model #04

	File 	Built with 	Oligo-State 	Ligands 	GMQE 	QMEAN
<https://swissmodel.expasy.org/interactive/3DmTPB/models/04.png> 	PDB
<https://swissmodel.expasy.org/interactive/3DmTPB/models/04.pdb>
ProMod3 3.2.0 	monomer 	
None
	0.02 	-3.59

QMEAN	
Created with Raphaël 2.2.0
	-3.59
Cβ	
Created with Raphaël 2.2.0
	-2.68
All Atom	
Created with Raphaël 2.2.0
	-0.86
solvation	
Created with Raphaël 2.2.0
	-2.36
torsion	
Created with Raphaël 2.2.0
	-2.07

	
Created with Raphaël 2.2.0Residue Number
<#lq-chart-04> Created with Raphaël 2.2.0Local Quality EstimatePredicted
Local Similarity to TargetResidue
Number1.00.80.60.40.20.0140150160170180190200
	
Created with Raphaël 2.2.0★Protein Size (Residues)
<#qn-chart-04> Created with Raphaël 2.2.0★Comparison with Non-redundant
Set of PDB StructuresNormalized QMEAN4 ScoreProtein Size
(Residues)1002003004005000.00.51.01.5

Template 	Seq Identity 	Oligo-state 	QSQE 	Found by 	Method
Resolution 	Seq Similarity 	Range 	Coverage 	Description
4v98.1.F <https://swissmodel.expasy.org/templates/4v98.1> 	9.38
monomer 	0.00 	HHblits 	X-ray 	3.10Å 	0.27 	139 - 202 	0.13 	CG10419


      The template contained no ligands.


Target    MTSLSKSFMQSGRICAACFYLLFTLLSIPISFKVGGLECGLSFTVTLFTLYFITTTLNVLARRHGGRLYIFFTNCLYYSQ
4v98.1.F  --------------------------------------------------------------------------------

Target    HFIIASLLYLFLSGFSNDELGNVLKNKYNESESFLEALKNSLNSNQINYVLYYYYYRFVVQPWQFVLTKSTPFFTLSEGF
4v98.1.F  ----------------------------------------------------------DQEKWKEFCRNQQPLLSTLLHL

Target    FTILAIQAVGETNRWLSNDLNS---------NTWIISSLLTSGGVITASLYYLYRIYVTPIWPLSIQTASLLGLVLSMVC
4v98.1.F  TQNDLELLLEMLSKWLQDPNTTVDLLHDVWLARWLYATLVCLHLPLEPHVF-----------------------------

Target    GLGLYGIVSQKGSVIESSLFFAYIVRCIYEISPKLATTATDEILNLFKDVWQKHQRNLPTADNLLCYFHNVILKNAEVLW
4v98.1.F  --------------------------------------------------------------------------------

Target    GSFIPRGRKKTGDFHDKLISILSFEKVSLISKPFWKFFKNFTFSVPLSINEFCQVTIKMASESVSPAIVINLCFRVLMFY
4v98.1.F  --------------------------------------------------------------------------------

Target    SATRIIPALQRKNDKQLRKSRRIMKGLYWYSPCILIAMYTHLILQYSGELKKDLCIWGCSEKWFGVDQPEIIVDSWGFWN
4v98.1.F  --------------------------------------------------------------------------------

Target    WCNIFCTILVYATELIGSGS
4v98.1.F  --------------------


------------------------------------------------------------------------


      Model #03

	File 	Built with 	Oligo-State 	Ligands 	GMQE 	QMEAN
<https://swissmodel.expasy.org/interactive/3DmTPB/models/03.png> 	PDB
<https://swissmodel.expasy.org/interactive/3DmTPB/models/03.pdb>
ProMod3 3.2.0 	monomer 	
None
	0.01 	-3.25

QMEAN	
Created with Raphaël 2.2.0
	-3.25
Cβ	
Created with Raphaël 2.2.0
	-3.09
All Atom	
Created with Raphaël 2.2.0
	-0.68
solvation	
Created with Raphaël 2.2.0
	-1.17
torsion	
Created with Raphaël 2.2.0
	-2.03

	
Created with Raphaël 2.2.0Residue Number
<#lq-chart-03> Created with Raphaël 2.2.0Local Quality EstimatePredicted
Local Similarity to TargetResidue
Number1.00.80.60.40.20.0140150160170180190200
	
Created with Raphaël 2.2.0★Protein Size (Residues)
<#qn-chart-03> Created with Raphaël 2.2.0★Comparison with Non-redundant
Set of PDB StructuresNormalized QMEAN4 ScoreProtein Size
(Residues)1002003004005000.00.51.01.5

Template 	Seq Identity 	Oligo-state 	QSQE 	Found by 	Method
Resolution 	Seq Similarity 	Range 	Coverage 	Description
6p6i.1.A <https://swissmodel.expasy.org/templates/6p6i.1> 	8.70
monomer 	0.00 	HHblits 	EM 	- 	0.23 	137 - 204 	0.14 	inner membrane
ABC-transporter


      The template contained no ligands.


Target    MTSLSKSFMQSGRICAACFYLLFTLLSIPISFKVGGLECGLSFTVTLFTLYFITTTLNVLARRHGGRLYIFFTNCLYYSQ
6p6i.1.A  --------------------------------------------------------------------------------

Target    HFIIASLLYLFLSGFSNDELGNVLKNKYNESESFLEALKNSLNSNQINYVLYYYYYRFVVQPWQFVLTKSTPFFTLSEGF
6p6i.1.A  -----------------------------------------------------PLWQVITPVRRKVILA--MALAGLAAL

Target    FTILAIQAVGETNRWLSNDLNSNTWIISSLLTSGGVITASLYYLYRIYVTPIWPLSIQTASLLGLVLSMVCGLGLYGIVS
6p6i.1.A  TSLGALLFLAWSLRDIRATPDAIPAWPLGGVIGCVVLTFVLRLQ------------------------------------

Target    QKGSVIESSLFFAYIVRCIYEISPKLATTATDEILNLFKDVWQKHQRNLPTADNLLCYFHNVILKNAEVLWGSFIPRGRK
6p6i.1.A  --------------------------------------------------------------------------------

Target    KTGDFHDKLISILSFEKVSLISKPFWKFFKNFTFSVPLSINEFCQVTIKMASESVSPAIVINLCFRVLMFYSATRIIPAL
6p6i.1.A  --------------------------------------------------------------------------------

Target    QRKNDKQLRKSRRIMKGLYWYSPCILIAMYTHLILQYSGELKKDLCIWGCSEKWFGVDQPEIIVDSWGFWNWCNIFCTIL
6p6i.1.A  --------------------------------------------------------------------------------

Target    VYATELIGSGS
6p6i.1.A  -----------


------------------------------------------------------------------------


    Materials and Methods


    Template Search

Template search with BLAST and HHblits has been performed against the
SWISS-MODEL template library (SMTL, last update: 2021-02-17, last
included PDB release: 2021-02-12).

The target sequence was searched with BLAST against the primary amino
acid sequence contained in the SMTL.

An initial HHblits profile has been built using the procedure outlined
in (Steinegger et al. <#hhblits>), followed by 1 iteration of HHblits
against Uniclust30 (Mirdita, von den Driesch et al. <#uniclust>). The
obtained profile has then be searched against all profiles of the SMTL.
A total of 20 templates were found.


    Template Selection

For each identified template, the template's quality has been predicted
from features of the target-template alignment. The templates with the
highest quality have then been selected for model building.


    Model Building

Models are built based on the target-template alignment using ProMod3
(Studer et al. <#promod3>). Coordinates which are conserved between the
target and the template are copied from the template to the model.
Insertions and deletions are remodelled using a fragment library. Side
chains are then rebuilt. Finally, the geometry of the resulting model is
regularized by using a force field.


    Model Quality Estimation

The global and per-residue model quality has been assessed using the
QMEAN scoring function (Studer et al. <#qmean>).


    Ligand Modelling

Ligands present in the template structure are transferred by homology to
the model when the following criteria are met: (a) The ligands are
annotated as biologically relevant in the template library, (b) the
ligand is in contact with the model, (c) the ligand is not clashing with
the protein, (d) the residues in contact with the ligand are conserved
between the target and the template. If any of these four criteria is
not satisfied, a certain ligand will not be included in the model. The
model summary includes information on why and which ligand has not been
included.


    Oligomeric State Conservation

The quaternary structure annotation of the template is used to model the
target sequence in its oligomeric form. The method (Bertoni et al.
<#qsqe>) is based on a supervised machine learning algorithm, Support
Vector Machines (SVM), which combines interface conservation, structural
clustering, and other template features to provide a quaternary
structure quality estimate (QSQE). The QSQE score is a number between 0
and 1, reflecting the expected accuracy of the interchain contacts for a
model built based a given alignment and template. Higher numbers
indicate higher reliability. This complements the GMQE score which
estimates the accuracy of the tertiary structure of the resulting model.


    References

  * *BLAST*
    Camacho, C., Coulouris, G., Avagyan, V., Ma, N., Papadopoulos, J.,
    Bealer, K., Madden, T.L. BLAST+: architecture and applications. BMC
    Bioinformatics 10, 421-430 (2009).
    <https://pubmed.ncbi.nlm.nih.gov/20003500>
    <https://dx.doi.org/10.1186/1471-2105-10-421>
  * *HHblits*
    Steinegger, M., Meier, M., Mirdita, M., Vöhringer, H., Haunsberger,
    S. J., Söding, J. HH-suite3 for fast remote homology detection and
    deep protein annotation. BMC Bioinformatics 20, 473 (2019).
    <https://pubmed.ncbi.nlm.nih.gov/31521110>
    <https://dx.doi.org/10.1186/s12859-019-3019-7>
  * *Uniclust30*
    Mirdita, M., von den Driesch, L., Galiez, C., Martin, M.J., Söding,
    J., Steinegger, M. Uniclust databases of clustered and deeply
    annotated protein sequences and alignments. Nucleic Acids Research
    45, D170–D176 (2016). <https://pubmed.ncbi.nlm.nih.gov/27899574>
    <https://dx.doi.org/10.1093/nar/gkw1081>


    Table T1:

Primary amino acid sequence for which templates were searched and models
were built.

MTSLSKSFMQSGRICAACFYLLFTLLSIPISFKVGGLECGLSFTVTLFTLYFITTTLNVLARRHGGRLYIFFTNCLYYSQHFIIASLLYLFLSGFSNDEL
GNVLKNKYNESESFLEALKNSLNSNQINYVLYYYYYRFVVQPWQFVLTKSTPFFTLSEGFFTILAIQAVGETNRWLSNDLNSNTWIISSLLTSGGVITAS
LYYLYRIYVTPIWPLSIQTASLLGLVLSMVCGLGLYGIVSQKGSVIESSLFFAYIVRCIYEISPKLATTATDEILNLFKDVWQKHQRNLPTADNLLCYFH
NVILKNAEVLWGSFIPRGRKKTGDFHDKLISILSFEKVSLISKPFWKFFKNFTFSVPLSINEFCQVTIKMASESVSPAIVINLCFRVLMFYSATRIIPAL
QRKNDKQLRKSRRIMKGLYWYSPCILIAMYTHLILQYSGELKKDLCIWGCSEKWFGVDQPEIIVDSWGFWNWCNIFCTILVYATELIGSGS


    Table T2:

Template 	Seq Identity 	Oligo-state 	QSQE 	Found by 	Method
Resolution 	Seq Similarity 	Coverage 	Description
6sp2.1.A 	15.25 	monomer 	- 	HHblits 	EM 	NA 	0.27 	0.24 	Membrane
protein TMS1d
6v4l.1.E 	18.75 	monomer 	- 	HHblits 	X-ray 	3.80Å 	0.27 	0.16 	Trk
system potassium uptake protein TrkH
6v4k.1.D 	18.75 	monomer 	- 	HHblits 	X-ray 	3.53Å 	0.27 	0.16 	Trk
system potassium uptake protein
6v4k.1.B 	18.75 	monomer 	- 	HHblits 	X-ray 	3.53Å 	0.27 	0.16 	Trk
system potassium uptake protein
6v4j.1.D 	18.75 	monomer 	- 	HHblits 	EM 	NA 	0.27 	0.16 	Trk system
potassium uptake protein TrkH
6p6i.1.A 	8.70 	monomer 	- 	HHblits 	EM 	NA 	0.23 	0.14 	inner membrane
ABC-transporter
6p6j.1.A 	8.70 	monomer 	- 	HHblits 	EM 	NA 	0.23 	0.14 	inner membrane
ABC-transporter
6v4j.1.B 	18.75 	monomer 	- 	HHblits 	EM 	NA 	0.27 	0.16 	Trk system
potassium uptake protein TrkH
4j9u.1.A 	18.75 	monomer 	- 	HHblits 	X-ray 	3.80Å 	0.27 	0.16 	Trk
system potassium uptake protein TrkH
6v4k.1.A 	18.75 	monomer 	- 	HHblits 	X-ray 	3.53Å 	0.27 	0.16 	Trk
system potassium uptake protein
6v4k.1.C 	18.75 	monomer 	- 	HHblits 	X-ray 	3.53Å 	0.27 	0.16 	Trk
system potassium uptake protein
4v98.1.F 	9.38 	monomer 	- 	HHblits 	X-ray 	3.10Å 	0.27 	0.13 	CG10419
6wvg.1.A 	12.07 	monomer 	- 	HHblits 	X-ray 	2.90Å 	0.28 	0.12 	Green
fluorescent protein, Leukocyte surface antigen CD53 chimera
6t0b.1.Y 	22.58 	monomer 	- 	HHblits 	EM 	NA 	0.31 	0.06 	Cytochrome c
oxidase polypeptide 5B, mitochondrial
6t0b.1.b 	22.58 	monomer 	- 	HHblits 	EM 	NA 	0.31 	0.06 	Cytochrome c
oxidase polypeptide 5B, mitochondrial
6t15.1.Y 	22.58 	monomer 	- 	HHblits 	EM 	NA 	0.31 	0.06 	CYTOCHROME C
OXIDASE POLYPEPTIDE 5B, MITOCHONDRIAL; SYNONYM: CYTOCHROME C OXIDASE
POLYPEPTIDE VB, COX5B


The table above shows the top 16 filtered templates. A further 3
templates were found which were considered to be less suitable for
modelling than the filtered list.
3pjz.1.A, 6k4j.1.A, 6wwz.1.F
Swiss Institute of Bioinformatics <https://www.sib.swiss/>
